Quetiapine-Induced Central Hypothyroidism

J Am Acad Child Adolesc Psychiatry. 2020 May;59(5):575-576. doi: 10.1016/j.jaac.2020.01.018. Epub 2020 Feb 6.


Hypothyroidism has been associated with quetiapine, but the underlying mechanism is not well understood and has been presumed to result from thyroid gland dysfunction (primary hypothyroidism). We present a case of symptomatic quetiapine-induced hypothyroidism due to hypothalamic/pituitary gland dysfunction (central [secondary] hypothyroidism).

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Humans
  • Hypothyroidism* / chemically induced
  • Quetiapine Fumarate / adverse effects


  • Quetiapine Fumarate