Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 1 (6), 468-479
eCollection

Lifestyle Modification in NAFLD/NASH: Facts and Figures

Affiliations
Review

Lifestyle Modification in NAFLD/NASH: Facts and Figures

Kate Hallsworth et al. JHEP Rep.

Abstract

The development of non-alcoholic fatty liver disease is closely linked to lifestyle factors, namely excessive caloric intake coupled with reduced physical activity and exercise. This review aims to examine the evidence behind lifestyle change as a tool to improve hepatic steatosis and liver histology in patients with non-alcoholic fatty liver disease/non-alcoholic steatohepatitis. Furthermore, potential barriers to adopting lifestyle changes and strategies to overcome these barriers in the clinical setting are discussed.

Keywords: diet; lifestyle; non-alcoholic fatty liver disease; non-alcoholic steatohepatitis; physical activity/exercise; weight loss.

Figures

Fig. 1
Fig. 1
Summary of the lifestyle treatment options through the course of NAFLD (modified from115). NAFLD, non-alcoholic fatty liver disease; NASH, non-alcoholic steatohepatitis.
Fig. 2
Fig. 2
Extrahepatic benefits of physical activity and exercise for patients with NAFLD. Physical activity and exercise offer a host of extrahepatic benefits for patients with NAFLD across the disease spectrum and are useful tools to aid weight-loss maintenance. Increasing cardiorespiratory fitness and muscle strength can help to maintain and improve the ability to perform day-to-day activities and thus improve quality of life. NAFLD, non-alcoholic fatty liver disease.
Fig. 3
Fig. 3
Useful techniques to support patients to make and sustain lifestyle changes,,,

Similar articles

See all similar articles

References

    1. Collaboration NCDRF Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants. Lancet. 2016;387:1377–1396. - PubMed
    1. Li J, Zou B, Yeo YH, Feng Y, Xie X, Lee DH. Prevalence, incidence, and outcome of non-alcoholic fatty liver disease in Asia, 1999-2019: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2019;4:389–398. - PubMed
    1. Gepner Y, Shelef I, Komy O, Cohen N, Schwarzfuchs D, Bril N. The beneficial effects of Mediterranean diet over low-fat diet may be mediated by decreasing hepatic fat content. J Hepatol. 2019;71:379–388. - PubMed
    1. St George A, Bauman A, Johnston A, Farrell G, Chey T, George J. Effect of a lifestyle intervention in patients with abnormal liver enzymes and metabolic risk factors. J Gastroenterol Hepatol. 2009;24:399–407. - PubMed
    1. Sun WH, Song MQ, Jiang CQ, Xin YN, Ma JL, Liu YX. Lifestyle intervention in non-alcoholic fatty liver disease in Chengyang District, Qingdao, China. World J Hepatol. 2012;4:224–230. - PMC - PubMed

LinkOut - more resources

Feedback