Cases: Three patients were referred to our musculoskeletal oncology service after undergoing autologous fat grafting procedures. Two masses were suspected to be "soft tissue sarcomas," and one was due to a mass of unknown origin. These findings have not been reported in the orthopedic literature and may generate potential referrals for orthopedic oncologists.
Conclusions: Awareness of potential complications of procedures from other surgical specialties and their radiographic characteristics is of utmost importance. The clinical and radiographic findings that could assist in distinguishing a mass related to an autologous fat transfer procedure from a soft tissue sarcoma are described.