Application of circulating tumor DNA in breast cancer

Breast J. 2020 Sep;26(9):1797-1800. doi: 10.1111/tbj.13775. Epub 2020 Feb 12.

Abstract

Precision medicine has been well recognized since it was proposed, and the invention of liquid biopsy meets the needs of this era. Circulating tumor DNA (ctDNA), one of the most promising components of liquid biopsies, has quickly become the focus of research in recent years because of its unique advantages in clinical application. This article reviews the clinical application of ctDNA in breast cancer detection in recent years and its potential clinical value.

Keywords: breast cancer; circulating tumor DNA; liquid biopsy; precision medicine.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomarkers, Tumor / genetics
  • Breast Neoplasms* / genetics
  • Circulating Tumor DNA* / genetics
  • Female
  • Humans
  • Liquid Biopsy
  • Neoplastic Cells, Circulating*
  • Precision Medicine

Substances

  • Biomarkers, Tumor
  • Circulating Tumor DNA