Urine dipstick for predicting intrapartum recto-vaginal colonisation by group B streptococci

Dan Med J. 2020 Feb;67(2):A08190466.


Introduction: In pregnant women, bacteriuria with group B streptococci (GBS) may be associated with a high degree of recto-vaginal GBS colonisation and therefore an increased risk of early-onset GBS disease. The aim of this study was to assess the performance of routine use of dipstick urine analysis during pregnancy for prediction of recto-vaginal GBS colonisation at the time of labour.

Methods: Among 902 unselected Danish pregnant women, we obtained results from 1) dipstick urine analysis, 2) urine culture carried out during pregnancy, if indicated, and 3) recto-vaginal culture at labour. The inclusion criteria were age > 18 years and gestational age ≥ 37 weeks.

Results: Intrapartum recto-vaginal GBS colonisation was predicted by a positive urine dipstick with 5% sensitivity only.

Conclusion: Dipstick urine analysis had a low sensitivity for predicting intrapartum recto-vaginal colonisation with GBS.

Funding: none.

Trial registration: not relevant.

MeSH terms

  • Adolescent
  • Adult
  • Bacteriuria / microbiology*
  • Colony Count, Microbial
  • Female
  • Gestational Age
  • Humans
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis*
  • Pregnancy Complications, Infectious / urine
  • Rectum / microbiology
  • Streptococcal Infections / diagnosis*
  • Streptococcal Infections / urine
  • Streptococcus agalactiae / isolation & purification*
  • Urinalysis*
  • Vagina / microbiology
  • Young Adult