A rare BRAF V600E mutation detected by next-generation sequencing in a superficial spreading melanoma: case report and potential diagnostic implications

J Eur Acad Dermatol Venereol. 2020 Aug;34(8):e393-e395. doi: 10.1111/jdv.16294. Epub 2020 May 15.

Authors

I Proietti^#¹, S Michelini^#¹, M Di Fraia¹, A Mambrin¹, V Petrozza², N Porta², L Pacini³, A Calogero³, N Skroza¹, C Potenza¹

Affiliations

¹ Dermatology Unit 'Daniele Innocenzi', Department of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy.
² Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University, Rome, Italy, Pathology Unit, I.C.O.T. Hospital, Latina, Italy.
³ Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University, Rome, Italy, UOS Diagnostica Molecolare Oncologica, Latina, Italy.

^# Contributed equally.

No abstract available

Publication types

Case Reports
Letter

MeSH terms

DNA Mutational Analysis
High-Throughput Nucleotide Sequencing
Humans
Melanoma* / diagnosis
Melanoma* / genetics
Mutation
Proto-Oncogene Proteins B-raf / genetics
Skin Neoplasms* / diagnosis
Skin Neoplasms* / genetics

Substances

BRAF protein, human
Proto-Oncogene Proteins B-raf