Electrochemical immunosensors for the detection of cytokine tumor necrosis factor alpha: A review

Hayati Filik; Asiye Aslıhan Avan

doi:10.1016/j.talanta.2020.120758

Electrochemical immunosensors for the detection of cytokine tumor necrosis factor alpha: A review

Talanta. 2020 May 1:211:120758. doi: 10.1016/j.talanta.2020.120758. Epub 2020 Jan 17.

Authors

Hayati Filik¹, Asiye Aslıhan Avan²

Affiliations

¹ Istanbul University-Cerrahpaşa, Faculty of Engineering, Department of Chemistry, 34320, Avcılar, Istanbul, Turkey. Electronic address: filik@istanbul.edu.tr.
² Istanbul University-Cerrahpaşa, Faculty of Engineering, Department of Chemistry, 34320, Avcılar, Istanbul, Turkey.

PMID: 32070602
DOI: 10.1016/j.talanta.2020.120758

Abstract

In this review, we focus on recent developments in nonlabeled@label-free and labeled@sandwich assay concepts of tumor necrosis factor-alpha (TNF-α) using numerous electrochemical approaches. The fundamental role of such nanostructured materials for the improvement of the analytical response and thus the analytical figures of merit of various TNF-α sensing operations were revealed. Also, this examination focused on recent developments in immuno-electrochemical cytokine TNF-α sensors based on nanostructured materials from 2006 to 2019.

Keywords: Cytokine; Determination; Electrochemistry; Fabrication; Immunosensor; Tumor necrosis factor-alpha.

Publication types

Review

MeSH terms

Biosensing Techniques / methods*
Cytokines / analysis*
Electrochemical Techniques / methods*
Electrodes
Humans
Immunoassay / methods*
Tumor Necrosis Factor-alpha / analysis*

Substances

Cytokines
Tumor Necrosis Factor-alpha