The relationship between the severity of erectile dysfunction and aortic stiffness

Andrologia. 2020 May;52(4):e13544. doi: 10.1111/and.13544. Epub 2020 Feb 18.

Abstract

Aortic stiffness increases in patients with erectile dysfunction (ED) but it is not known whether aortic stiffness affects the degree of ED. In the present study, we aimed to determine whether there is any relationship between aortic stiffness and the severity of ED. Patients with ED were divided into 3 groups according to the International Index of Erectile Function (IIEF) scores. Mild ED was named as group 1, moderate ED as group 2 and severe ED as group 3. The values of fasting blood glucose (FBG), serum lipid values, total testosterone (T. tes), and free testosterone (F tes) were recorded. Aortic stiffness was determined by pulse wave velocity (PWV) and augmentation index (AIX) measurements. The mean or median values of the laboratory parameters among the groups were similar (p > .05). No statistical difference was found between the groups in terms of AIX value (p = .386). Mean PWV values were calculated as 7.26, 8.30 and 8.78 in group 1, group 2 and group 3 respectively. PWV values were significantly different between groups (p < .0001). PWV values were found to be increased with increasing severity of erectile dysfunction.

Keywords: aortic stiffness; augmentation index; erectile dysfunction; pulse wave velocity.

MeSH terms

  • Erectile Dysfunction / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Severity of Illness Index
  • Vascular Stiffness*