Good, better, best? The effects of polarization on photobiomodulation therapy

J Biophotonics. 2020 May;13(5):e201960230. doi: 10.1002/jbio.201960230. Epub 2020 Feb 27.

Abstract

Photobiomodulation therapy (PBMT) is a widely adopted form of phototherapy used to treat many chronic conditions that effect the population at large. The exact physiological mechanisms of PBMT remain unsolved; however, the prevailing theory centres on changes in mitochondrial function. There are many irradiation parameters to consider when investigating PBMT, one of which is the state of polarization. There is some evidence to show that polarization of red and near-infrared light may promote different and/or increased biological activity when compared to otherwise identical non-polarized light. These enhanced cellular effects may also be present when the polarized light is applied linear to the tissue direction. Herein, we synthesize the current experimental and clinical evidence pertaining to polarized photobiomodulation therapy; ultimately, to better inform future research into this area of phototherapy.

Keywords: low-level light therapy; photobiomodulation; polarization; polarized light therapy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Low-Level Light Therapy*
  • Mitochondria
  • Phototherapy