[The immunomodulating action of myelopeptides in hypoxic hypoxia in animals]

D V Sarybaeva; L A Zakharova; A M Vasilenko; A A Mikhaĭlova; B T Tulebekov

[The immunomodulating action of myelopeptides in hypoxic hypoxia in animals]

Biull Eksp Biol Med. 1988 Dec;106(12):691-2.

[Article in Russian]

Authors

D V Sarybaeva, L A Zakharova, A M Vasilenko, A A Mikhaĭlova, B T Tulebekov

PMID: 3207877

Abstract

It was observed that in animals which underwent a hypoxic stress by way of a 3-day exposition in the pressure chamber at an altitude of 7,000 m the immune response to sheep erythrocytes was decreased by 47 per cent. A two-three-fold decrease in the production of myelopeptides was noted in 24h after the exposition in the pressure chamber.

Publication types

Comparative Study

MeSH terms

Adjuvants, Immunologic / isolation & purification
Adjuvants, Immunologic / therapeutic use*
Animals
Atmosphere Exposure Chambers
Bone Marrow / immunology*
Drug Evaluation, Preclinical
Female
Hypoxia / drug therapy*
Hypoxia / immunology
Immunization
Male
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Molecular Weight
Oligopeptides*
Peptide Biosynthesis
Peptides / isolation & purification
Peptides / therapeutic use*
Stress, Physiological / drug therapy
Stress, Physiological / immunology

Substances

Adjuvants, Immunologic
Oligopeptides
Peptides
myelopeptides