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Review
. 2020 Feb 17;9(2):546.
doi: 10.3390/jcm9020546.

Treatment With CPAP in Elderly Patients With Obstructive Sleep Apnoea

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Free PMC article
Review

Treatment With CPAP in Elderly Patients With Obstructive Sleep Apnoea

Tomas Posadas et al. J Clin Med. .
Free PMC article

Abstract

The population pyramid is changing as a result of the ever-increasing life expectancy, which makes it crucial to acquire an in-depth understanding of the diseases that most often affect the elderly. Obstructive sleep apnoea (OSA) affects 15%-20% of the population aged over 65 years. Despite this prevalence, there have been very few specific studies on the management of OSA in this age group, even though over 60% of the patients aged over 65-70 years who attend sleep units with suspicion of OSA receive treatment with continuous positive airway pressure (CPAP), on the basis of an extrapolation of the positive results achieved by CPAP in clinical trials involving middle-aged males. However, the latter's form of presentation, evolution and, probably, prognosis comparing with OSA are not the same as those of elderly patients. Recent clinical trials performed on an exclusive series of elderly patients have shed light on the possible role of CPAP treatment in elderly patients with OSA, but there are still many questions that need to be answered. The physiological increase in the number of sleep-related disorders with the passing of years, and the lack of validated diagnostic and therapeutic tools for this age group are probably the greatest obstacles to define, diagnose and treat OSA in the elderly.

Keywords: continuous positive airway pressure; elderly; obstructive sleep apnoea.

Conflict of interest statement

The authors have no conflicts of interest to declare related to this manuscript.

Figures

Figure 1
Figure 1
Kaplan-Meier curves according to age group for the percentage of patients with a CPAP compliance of at least four hours/day during follow-up. Martinez-Garcia et al. ERJ Open Res. 2019 Mar 4;5(1). pii: 00178-2018, with permission.

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