Enhancing Skin Grafts with Primed Gingival Mesenchymal Stromal Cells

J Invest Dermatol. 2020 Mar;140(3):519-520. doi: 10.1016/j.jid.2019.09.005.

Abstract

Injuries of the largest anatomical organ, the skin, resulting from trauma, burns, or inflammatory disorders can lead to devastating health effects. Modern approaches to re-establishing critical barrier functions have evolved from simple biomaterial dressings to sophisticated skin grafts. A report by Magne et al. (2019) describes the exciting use of IL-1β-pretreated gingival mesenchymal stem cells to enhance skin graft functions.

Publication types

  • Comment

MeSH terms

  • Matrix Metalloproteinases
  • Mesenchymal Stem Cell Transplantation*
  • Mesenchymal Stem Cells*
  • Skin Transplantation
  • Transforming Growth Factors
  • Wound Healing

Substances

  • Transforming Growth Factors
  • Matrix Metalloproteinases