Metabolic rate in sedentary adults, following different exercise training interventions: The FIT-AGEING randomized controlled trial

Clin Nutr. 2020 Nov;39(11):3230-3240. doi: 10.1016/j.clnu.2020.02.001. Epub 2020 Feb 8.

Abstract

Background & aims: This study compares the influence of different exercise training programs on basal metabolic rate (BMR) and fat oxidation, in basal conditions (BFox) and during exercise (MFO), in sedentary, middle-aged adults.

Methods: The study subjects of this 12 week-long, randomised controlled trial, were 71 middle-aged adults (age 53.5 ± 4.9 years; 52% women). Subjects were randomly assigned to one of the following groups: (1) no exercise, (2) concurrent training based on international physical activity recommendations (PAR group), (3) high intensity interval training (HIIT group), and (4) high intensity interval training plus whole-body electromyostimulation (HIIT + EMS group). Subject BMR, BFox and MFO were determined by indirect calorimetry before and after the intervention.

Results: The HIIT + EMS subjects showed significant increases in BFox following the intervention compared with the control group (all P = 0.043); no such differences were seen in the PAR and HIIT compared with the control group (all P ≥ 0.1). A significant increase in post-intervention MFO was noted for the HIIT and HIIT + EMS group compared to the non-exercise control group (P < 0.05); no such difference was seen in the PAR group compared to the control group (all P ≥ 0.05).

Conclusions: Twelve weeks of high intensity interval training plus whole-body electromyostimulation may increase the BFox and MFO of middle-aged sedentary adults. These findings have important clinical implications; a well-designed high-intensity interval training program plus whole-body electromyostimulation might be followed to help combat the appearance of chronic metabolic diseases characterized by metabolic inflexibility in middle-aged sedentary adults, though it will be necessary to determine how long the effects last.

Keywords: Concurrent training; Energy expenditure; Energy metabolism; HIIT; Metabolic flexibility; WB-EMS.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Physiological / physiology
  • Adipose Tissue / metabolism
  • Basal Metabolism / physiology*
  • Calorimetry, Indirect
  • Electric Stimulation Therapy / methods*
  • Energy Metabolism
  • Exercise / physiology*
  • Exercise Therapy / methods*
  • Female
  • High-Intensity Interval Training / methods
  • Humans
  • Male
  • Middle Aged
  • Oxidation-Reduction
  • Oxygen Consumption
  • Sedentary Behavior*