Screening guidelines and recommendations for patients at high risk of developing endocrine cancers

J Surg Oncol. 2020 May;121(6):975-983. doi: 10.1002/jso.25869. Epub 2020 Feb 23.


Screening guidelines in patients with inherited endocrine syndromes and others at high risk for developing endocrine cancers have significant implications as early tumor detection is associated with improved outcomes. Given the unique challenges in diagnosis and treatment, patients at high risk for developing endocrine cancers require multidisciplinary care. The complexity of decision making and rarity of these syndromes support referral to high-volume centers with the experience and knowledge to treat these at-risk patients.

Keywords: Carney complex; MEN; NF1; VHL; pancreatic cancer.

Publication types

  • Review

MeSH terms

  • Carcinoma, Pancreatic Ductal / diagnosis
  • Early Detection of Cancer / methods
  • Endocrine Gland Neoplasms / diagnosis*
  • Humans
  • Multiple Endocrine Neoplasia / diagnosis*
  • Pancreatic Neoplasms / diagnosis
  • Practice Guidelines as Topic
  • Thyroid Neoplasms / diagnosis