What Will Computational Modeling Approaches Have to Say in the Era of Atomistic Cryo-EM Data?

J Chem Inf Model. 2020 May 26;60(5):2410-2412. doi: 10.1021/acs.jcim.0c00123. Epub 2020 Feb 24.


The focus of this viewpoint is to identify, in the era of atomistic resolution cryo-electron microscopy data, the areas in which computational modelling and molecular simulations will bring valuable contributions to structural biologists and to give an overview of some of the existing efforts in this direction.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cryoelectron Microscopy*
  • Models, Molecular
  • Protein Conformation