Human Exposure to Hantaviruses Associated with Rodents of the Murinae Subfamily, Madagascar

Emerg Infect Dis. 2020 Mar;26(3):587-590. doi: 10.3201/eid2603.190320.

Abstract

We conducted a national human serologic study of a hantavirus detected in Madagascar rodents using a commercial kit and a new ELISA targeting the virus. Our results suggest a conservative estimate of 2.7% (46/1,680) IgG seroprevalence. A second single-district study using the new ELISA revealed a higher prevalence (7.2%; 10/139).

Keywords: Madagascar; Murinae; hantavirus; human population; rodents; seroprevalence; viruses; zoonoses.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Animals
  • Child
  • Child, Preschool
  • Disease Reservoirs
  • Female
  • Hantavirus Infections / epidemiology*
  • Hantavirus Infections / transmission
  • Humans
  • Madagascar / epidemiology
  • Male
  • Mice / virology
  • Middle Aged
  • Prevalence
  • Retrospective Studies
  • Young Adult
  • Zoonoses