Analysis of angiotensin-converting enzyme 2 (ACE2) from different species sheds some light on cross-species receptor usage of a novel coronavirus 2019-nCoV

J Infect. 2020 Apr;80(4):469-496. doi: 10.1016/j.jinf.2020.02.013. Epub 2020 Feb 21.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Angiotensin-Converting Enzyme 2
  • Animals
  • Betacoronavirus* / metabolism
  • COVID-19
  • Coronavirus Infections / transmission
  • Coronavirus Infections / virology
  • Humans
  • Models, Molecular
  • Pandemics
  • Peptidyl-Dipeptidase A / chemistry*
  • Peptidyl-Dipeptidase A / metabolism
  • Pneumonia, Viral / transmission
  • Pneumonia, Viral / virology
  • Protein Conformation
  • Receptors, Coronavirus
  • Receptors, Virus / chemistry*
  • Receptors, Virus / metabolism
  • SARS-CoV-2
  • Sequence Alignment
  • Species Specificity

Substances

  • Receptors, Coronavirus
  • Receptors, Virus
  • Peptidyl-Dipeptidase A
  • ACE2 protein, human
  • Angiotensin-Converting Enzyme 2