Genetic diversity and evolution of SARS-CoV-2

Infect Genet Evol. 2020 Jul;81:104260. doi: 10.1016/j.meegid.2020.104260. Epub 2020 Feb 21.


COVID-19 is a viral respiratory illness caused by a new coronavirus called SARS-CoV-2. The World Health Organization declared the SARS-CoV-2 outbreak a global public health emergency. We performed genetic analyses of eighty-six complete or near-complete genomes of SARS-CoV-2 and revealed many mutations and deletions on coding and non-coding regions. These observations provided evidence of the genetic diversity and rapid evolution of this novel coronavirus.

Keywords: Coronavirus; Genomic diversity; Mutations; SARS-CoV-2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Betacoronavirus / classification*
  • Betacoronavirus / genetics*
  • Evolution, Molecular*
  • Genetic Variation*
  • Genome, Viral / genetics*
  • Mutation
  • SARS-CoV-2
  • Sequence Deletion / genetics