Electronic medication monitors help determine adherence subgroups in asthma

Heather E H De Keyser; Leanne Kaye; William C Anderson; Rahul Gondalia; Ben Theye; Stanley J Szefler; David A Stempel

doi:10.1016/j.rmed.2020.105914

Electronic medication monitors help determine adherence subgroups in asthma

Respir Med. 2020 Apr:164:105914. doi: 10.1016/j.rmed.2020.105914. Epub 2020 Feb 19.

Authors

Heather E H De Keyser¹, Leanne Kaye², William C Anderson³, Rahul Gondalia⁴, Ben Theye⁵, Stanley J Szefler⁶, David A Stempel⁷

Affiliations

¹ Department of Pediatrics, Sections of Allergy and Immunology and Pulmonary and Sleep Medicine, University of Colorado School of Medicine and the Breathing Institute, Children's Hospital Colorado, 13123, East 16th Ave, Aurora, CO, 80045, USA. Electronic address: heather.dekeyser@childrenscolorado.org.
² Propeller Health, 47 Maiden Lane, Floor 3, San Francisco, CA, 94108, USA. Electronic address: leanne.kaye@propellerhealth.com.
³ Department of Pediatrics, Sections of Allergy and Immunology and Pulmonary and Sleep Medicine, University of Colorado School of Medicine and the Breathing Institute, Children's Hospital Colorado, 13123, East 16th Ave, Aurora, CO, 80045, USA. Electronic address: William.Anderson@childrenscolorado.org.
⁴ Propeller Health, 47 Maiden Lane, Floor 3, San Francisco, CA, 94108, USA. Electronic address: rahul.gondalia@propellerhealth.com.
⁵ Propeller Health, 47 Maiden Lane, Floor 3, San Francisco, CA, 94108, USA.
⁶ Department of Pediatrics, Sections of Allergy and Immunology and Pulmonary and Sleep Medicine, University of Colorado School of Medicine and the Breathing Institute, Children's Hospital Colorado, 13123, East 16th Ave, Aurora, CO, 80045, USA. Electronic address: Stanley.Szefler@childrenscolorado.org.
⁷ Propeller Health, 47 Maiden Lane, Floor 3, San Francisco, CA, 94108, USA. Electronic address: david.stempel@propellerhealth.com.

PMID: 32094102
DOI: 10.1016/j.rmed.2020.105914

Abstract

Non-adherence to treatment regimens in asthma is well described, however less is known about temporal patterns of medication use. We monitored 20 weeks of controller medication use and analyzed these patterns in patients ≥4 years of age with self-reported asthma enrolled in a digital health program. At baseline, approximately 20%, 28%, 25% and 27% of patients had optimal, moderate, sub-optimal and poor adherence, respectively. Medication adherence decreased in all groups in this study. The largest absolute decreases in adherence (-32%) were observed for moderately adherent patients. Certain adherence patterns which demonstrated greater declines, that, once identified, could be intervened upon.

Keywords: Adherence; Asthma; Electronic medication monitoring.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Administration, Inhalation
Adult
Asthma / drug therapy*
Female
Humans
Male
Medication Adherence / statistics & numerical data*
Monitoring, Physiologic*
Young Adult