The omentum, a niche for premetastatic ovarian cancer

J Exp Med. 2020 Apr 6;217(4):e20192312. doi: 10.1084/jem.20192312.

Abstract

The work by Etzerodt et al. in this issue of JEM (https://doi.org/10.1084/jem.20191869) identifies a distinct omentum-resident macrophage population of embryonic origin and demonstrates that these cells provide a niche for ovarian cancer metastasis and cancer stemness. This research opens up for many questions and therapeutic prospects.

Publication types

  • Comment

MeSH terms

  • Female
  • Humans
  • Macrophages
  • Omentum*
  • Ovarian Neoplasms*