Effects of continuous distending pressure on lung volumes and lung mechanics in the immediate neonatal period

Biol Neonate. 1977;31(1-2):111-5. doi: 10.1159/000240950.


The effects of CPAP and CNEP on lung mechanics and lung volumes were investigated in a group of 12 healthy newborn infants. Both resulted in a mild suppression of respiration. The fall in TPR50 was far greater during CPAP than during CNEP. Both led to a one third fall in dynamic compliance. Approximately 50% of the distending pressure was transmitted to the mediastinal structures whether applied as CPAP or CNEP.

MeSH terms

  • Airway Resistance
  • Heart Rate
  • Humans
  • Infant, Newborn*
  • Lung Compliance*
  • Lung Volume Measurements
  • Positive-Pressure Respiration* / adverse effects
  • Respiration*
  • Tidal Volume