Comparing Care of the Primary and Secondary Hemochromatosis Patients

J Infus Nurs. 2020 Mar/Apr;43(2):65-69. doi: 10.1097/NAN.0000000000000358.


Hemochromatosis is an imbalance of excessive serum iron and is a life-threatening condition if left untreated. Due to different causes, primary and secondary hemochromatosis have different patient care considerations for the infusion nurse. Understanding the pathophysiology and how the body absorbs iron is imperative for providing the highest quality care. Since primary (hereditary) hemochromatosis originates from a gene mutation, and secondary (acquired) from excessive intake, the treatment and education must be adjusted accordingly to deliver successful outcomes for both diagnoses.

Publication types

  • Comparative Study

MeSH terms

  • Deferiprone / therapeutic use*
  • Deferoxamine / therapeutic use*
  • Hemochromatosis / blood
  • Hemochromatosis / drug therapy*
  • Hemochromatosis / genetics
  • Hemochromatosis / physiopathology
  • Humans
  • Iron / adverse effects*
  • Iron / blood
  • Iron Chelating Agents / therapeutic use*
  • Mutation / genetics
  • Siderophores / therapeutic use*


  • Iron Chelating Agents
  • Siderophores
  • Deferiprone
  • Iron
  • Deferoxamine