What the systematic review of HPV vaccine clinical study reports does, and does not, reveal: commentary on Jørgensen et al

doi:10.1186/s13643-020-01299-5

Comment

. 2020 Feb 28;9(1):41.

doi: 10.1186/s13643-020-01299-5.

What the systematic review of HPV vaccine clinical study reports does, and does not, reveal: commentary on Jørgensen et al

Hilda Bastian¹

Affiliations

PMID: 32106882
PMCID: PMC7047360
DOI: 10.1186/s13643-020-01299-5

Free PMC article

Comment

What the systematic review of HPV vaccine clinical study reports does, and does not, reveal: commentary on Jørgensen et al

Hilda Bastian. Syst Rev. 2020.

Free PMC article

. 2020 Feb 28;9(1):41.

doi: 10.1186/s13643-020-01299-5.

Author

Hilda Bastian¹

Affiliation

¹ Bond University, Robina, Australia. hildabast@gmail.com.

PMID: 32106882
PMCID: PMC7047360
DOI: 10.1186/s13643-020-01299-5

No abstract available

Conflict of interest statement

I worked at IQWiG between 2004 and 2011, and where I participated in review of data on HPV vaccines as basis for information to the general public, and the development of the Institute’s scientific methods. IQWiG included CSRs in its drug evaluations. I have both collaborated, and been in disagreements, with two of the authors (PCG and TJ). In 2018, I blogged about the authors’ critique of the Cochrane review on HPV vaccines and the dispute between PCG and the Cochrane Collaboration.

Comment on

Benefits and harms of the human papillomavirus (HPV) vaccines: systematic review with meta-analyses of trial data from clinical study reports.
Jørgensen L, Gøtzsche PC, Jefferson T. Jørgensen L, et al. Syst Rev. 2020 Feb 28;9(1):43. doi: 10.1186/s13643-019-0983-y. Syst Rev. 2020. PMID: 32106879 Free PMC article.

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References

1. Jørgensen L, Gøtzsche PC, Jefferson T. Benefits and harms of the human papillomavirus (HPV) vaccines: systematic review with meta-analyses of trial data from clinical study reports. Syst Rev. 2020;9(1). 10.1186/s13643-019-0983-y.
1. Jørgensen L, Gøtzsche PC, Jefferson T. Benefits and harms of the human papillomavirus (HPV) vaccines: comparison of trial data from clinical study reports with corresponding trial register entries and journal publications. Syst Rev. 2020. 2020. Volume 9, Issue 1. 10.1186/s13643-020-01300-1
1. Jørgensen L, Doshi P, Gøtzsche PC, Jefferson T. Challenges of independent assessment of potential harms of HPV vaccine. BMJ. 2018;362:k3694. doi: 10.1136/bmj.k3694. - DOI - PubMed
1. Melander H, Ahlqvist-Rastad J, Meijer G, Beermann B. Evidence b(i)ased medicine—selective reporting from studies sponsored by pharmaceutical industry: review of studies in new drug applications. BMJ. 2003;326:1171–1173. doi: 10.1136/bmj.326.7400.1171. - DOI - PMC - PubMed
1. MacLean CH, Morton SC, Ofman JJ, et al. How useful are unpublished data from the Food and Drug Administration in meta-analysis? J Clin Epi. 2003;56(1):44–51. doi: 10.1016/S0895-4356(02)00520-6. - DOI - PubMed

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[1] Jørgensen L, Gøtzsche PC, Jefferson T. Benefits and harms of the human papillomavirus (HPV) vaccines: systematic review with meta-analyses of trial data from clinical study reports. Syst Rev. 2020;9(1). 10.1186/s13643-019-0983-y.

[2] Jørgensen L, Gøtzsche PC, Jefferson T. Benefits and harms of the human papillomavirus (HPV) vaccines: systematic review with meta-analyses of trial data from clinical study reports. Syst Rev. 2020;9(1). 10.1186/s13643-019-0983-y.

[3] Jørgensen L, Gøtzsche PC, Jefferson T. Benefits and harms of the human papillomavirus (HPV) vaccines: comparison of trial data from clinical study reports with corresponding trial register entries and journal publications. Syst Rev. 2020. 2020. Volume 9, Issue 1. 10.1186/s13643-020-01300-1

[4] Jørgensen L, Gøtzsche PC, Jefferson T. Benefits and harms of the human papillomavirus (HPV) vaccines: comparison of trial data from clinical study reports with corresponding trial register entries and journal publications. Syst Rev. 2020. 2020. Volume 9, Issue 1. 10.1186/s13643-020-01300-1

[5] Jørgensen L, Doshi P, Gøtzsche PC, Jefferson T. Challenges of independent assessment of potential harms of HPV vaccine. BMJ. 2018;362:k3694. doi: 10.1136/bmj.k3694. - DOI - PubMed

[6] Jørgensen L, Doshi P, Gøtzsche PC, Jefferson T. Challenges of independent assessment of potential harms of HPV vaccine. BMJ. 2018;362:k3694. doi: 10.1136/bmj.k3694. - DOI - PubMed

[7] Melander H, Ahlqvist-Rastad J, Meijer G, Beermann B. Evidence b(i)ased medicine—selective reporting from studies sponsored by pharmaceutical industry: review of studies in new drug applications. BMJ. 2003;326:1171–1173. doi: 10.1136/bmj.326.7400.1171. - DOI - PMC - PubMed

[8] Melander H, Ahlqvist-Rastad J, Meijer G, Beermann B. Evidence b(i)ased medicine—selective reporting from studies sponsored by pharmaceutical industry: review of studies in new drug applications. BMJ. 2003;326:1171–1173. doi: 10.1136/bmj.326.7400.1171. - DOI - PMC - PubMed

[9] MacLean CH, Morton SC, Ofman JJ, et al. How useful are unpublished data from the Food and Drug Administration in meta-analysis? J Clin Epi. 2003;56(1):44–51. doi: 10.1016/S0895-4356(02)00520-6. - DOI - PubMed

[10] MacLean CH, Morton SC, Ofman JJ, et al. How useful are unpublished data from the Food and Drug Administration in meta-analysis? J Clin Epi. 2003;56(1):44–51. doi: 10.1016/S0895-4356(02)00520-6. - DOI - PubMed

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What the systematic review of HPV vaccine clinical study reports does, and does not, reveal: commentary on Jørgensen et al

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What the systematic review of HPV vaccine clinical study reports does, and does not, reveal: commentary on Jørgensen et al

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