Optically pumped magnetoencephalography in epilepsy

Ann Clin Transl Neurol. 2020 Mar;7(3):397-401. doi: 10.1002/acn3.50995. Epub 2020 Feb 29.

Abstract

We demonstrate the first use of Optically Pumped Magnetoencephalography (OP-MEG) in an epilepsy patient with unrestricted head movement. Current clinical MEG uses a traditional SQUID system, where sensors are cryogenically cooled and housed in a helmet in which the patient's head is fixed. Here, we use a different type of sensor (OPM), which operates at room temperature and can be placed directly on the patient's scalp, permitting free head movement. We performed OP-MEG recording in a patient with refractory focal epilepsy. OP-MEG-identified analogous interictal activity to scalp EEG, and source localized this activity to an appropriate brain region.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Resistant Epilepsy / diagnosis
  • Drug Resistant Epilepsy / physiopathology
  • Electroencephalography
  • Epilepsies, Partial / diagnosis*
  • Epilepsies, Partial / physiopathology
  • Female
  • Humans
  • Magnetoencephalography / instrumentation*
  • Magnetoencephalography / methods
  • Middle Aged