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. 2020 Apr;76:71-76.
doi: 10.1016/j.ijsu.2020.02.034. Epub 2020 Feb 26.

World Health Organization Declares Global Emergency: A Review of the 2019 Novel Coronavirus (COVID-19)

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World Health Organization Declares Global Emergency: A Review of the 2019 Novel Coronavirus (COVID-19)

Catrin Sohrabi et al. Int J Surg. .
Free PMC article

Erratum in


An unprecedented outbreak of pneumonia of unknown aetiology in Wuhan City, Hubei province in China emerged in December 2019. A novel coronavirus was identified as the causative agent and was subsequently termed COVID-19 by the World Health Organization (WHO). Considered a relative of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), COVID-19 is caused by a betacoronavirus named SARS-CoV-2 that affects the lower respiratory tract and manifests as pneumonia in humans. Despite rigorous global containment and quarantine efforts, the incidence of COVID-19 continues to rise, with 90,870 laboratory-confirmed cases and over 3,000 deaths worldwide. In response to this global outbreak, we summarise the current state of knowledge surrounding COVID-19.

Keywords: COVID-19; Global health emergency; Novel coronavirus; Viral transmission; Wuhan.

Conflict of interest statement

Declaration of competing interest No conflicts of interest to declare.


Fig. 1
Fig. 1
Illustration of the geographical spread of confirmed COVID-19. Data accurate as of 3rd March 2020 [23].
Fig. 2
Fig. 2
Illustration of the SARS-CoV-2 virion [56].

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    1. Lu H., Stratton C.W., Tang Y. Outbreak of pneumonia of unknown etiology in wuhan China: the mystery and the miracle. J. Med. Virol. 2020:25678. - PMC - PubMed
    1. World Health Organization . 2020. WHO Director-General’s Remarks at the Media Briefing on 2019-nCoV on 11 February 2020.
    1. Chen N., Zhou M., Dong X. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020 - PMC - PubMed
    1. Wang D., Hu B., Hu C. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in wuhan, China. J. Am. Med. Assoc. 2020 - PMC - PubMed
    1. World Health Organization . 2020. Novel Coronavirus(2019-nCoV) Situation Report - 12.

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