Endometriosis, an estrogen-dependent inflammatory disease characterized by the ectopic presence of endometrial tissue, has been the topic of renewed research and debate in recent years. The paradigm shift from the belief that endometriosis only affects women of reproductive age has drawn attention to endometriosis in both premenarchal and postmenopausal patients. There is still scarce information in literature regarding postmenopausal endometriosis, the mostly studied and reported being the prevalence in postmenopausal women. Yet, other important issues also need to be addressed concerning diagnosis, pathophysiology, and management. We aimed at summarizing the currently available data in literature in order to provide a concise and precise update regarding information available on postmenopausal endometriosis.
Keywords: diagnosis; endometriosis; malignancy; management; menopause.
Conflict of interest statement
The authors declare no conflict of interest.
The management of menopause in women with a history of endometriosis: a systematic review.Hum Reprod Update. 2017 Jul 1;23(4):481-500. doi: 10.1093/humupd/dmx011. Hum Reprod Update. 2017. PMID: 28498913 Free PMC article. Review.
Endometriosis after menopause: physiopathology and management of an uncommon condition.Climacteric. 2017 Apr;20(2):138-143. doi: 10.1080/13697137.2017.1284781. Epub 2017 Feb 8. Climacteric. 2017. PMID: 28286987
Hormonal Replacement Therapy in Menopausal Women with History of Endometriosis: A Review of Literature.Medicina (Kaunas). 2019 Aug 14;55(8):477. doi: 10.3390/medicina55080477. Medicina (Kaunas). 2019. PMID: 31416164 Free PMC article. Review.
Endometriosis after menopause.Womens Health (Lond). 2015 Aug;11(5):711-5. doi: 10.2217/whe.15.59. Epub 2015 Sep 7. Womens Health (Lond). 2015. PMID: 26343168 Review.
Hormone therapy for endometriosis and surgical menopause.Cochrane Database Syst Rev. 2009 Jan 21;(1):CD005997. doi: 10.1002/14651858.CD005997.pub2. Cochrane Database Syst Rev. 2009. PMID: 19160262 Review.