Idiopathic cutaneous and renal glomerular vasculopathy of greyhounds

Abstract

An idiopathic disease involving skin and occasionally kidneys was seen in kenneled and racing greyhounds. Hemorrhages, fibrinoid arteritis, thrombosis, and infarction with deep, slowly healing ulcers characterized the skin lesions. Peracute renal glomerular necrosis, particularly involving afferent arterioles with intravascular coagulation in glomerular capillaries were the distinctive findings in affected kidneys. A complex pathogenesis of this disorder was suspected in which genetic predisposition plays a prominent role.