What we know so far: COVID-19 current clinical knowledge and research

Clin Med (Lond). 2020 Mar;20(2):124-127. doi: 10.7861/clinmed.2019-coron. Epub 2020 Mar 5.


In December 2019, health authorities in Wuhan, China, identified a cluster of pneumonia cases of unknown aetiology linked to the city's South China Seafood Market. Subsequent investigations revealed a novel coronavirus, SARS-CoV-2, as the causative agent now at the heart of a major outbreak. The rising case numbers have been accompanied by unprecedented public health action, including the wholesale isolation of Wuhan. Alongside this has been a robust scientific response, including early publication of the pathogen genome, and rapid development of highly specific diagnostics. This article will review the new knowledge of SARS-CoV-2 COVID-19 acute respiratory disease, and summarise its clinical features.

Keywords: 2019-nCoV; SARS-CoV-2; Wuhan; coronavirus; respiratory tract infection.

Publication types

  • Review

MeSH terms

  • Betacoronavirus
  • COVID-19
  • Coronavirus Infections* / diagnosis
  • Coronavirus Infections* / epidemiology
  • Coronavirus Infections* / therapy
  • Coronavirus Infections* / transmission
  • Disease Outbreaks*
  • Humans
  • Palliative Care
  • Pneumonia, Viral* / diagnosis
  • Pneumonia, Viral* / epidemiology
  • Pneumonia, Viral* / therapy
  • Pneumonia, Viral* / transmission
  • Public Health
  • Public Health Surveillance*
  • SARS-CoV-2
  • Severe Acute Respiratory Syndrome / epidemiology