[Advances on presymptomatic or asymptomatic carrier transmission of COVID-19]
- PMID: 32141279
- DOI: 10.3760/cma.j.cn112338-20200228-00207
[Advances on presymptomatic or asymptomatic carrier transmission of COVID-19]
Abstract
COVID-19 is rapidly spreading. Patients in incubation period and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is very lacking so far, although there are a few studies suggesting that presymptomatic or asymptomatic carrier may cause COVID-19 transmission. Nearly half of the literature is in the state of preprint without peer review. The question of "the degree to which presymptomatic or asymptomatic infections can transmit" is not fully understood. There is an urgent need to screen infected carriers in larger close contacts or in the general population, and assess their risk for transmission.
新型冠状病毒肺炎正快速向人群传播,潜伏期患者和隐性感染者都有向体外排出病毒而成为传染源的可能,但是由于临床症状隐匿,这类传染源无法有效识别,容易形成防控措施的漏洞。目前有研究提示该病潜伏期患者或隐性感染者可能造成疾病传播,但是研究仍然十分有限,而且近一半文献尚处于未经同行评审的预印本状态。对于"感染者能否在潜伏期传播病毒、无症状感染者是否可以传播病毒、效率如何",尚无明确且公认的回答。亟待在更大的密切接触者或者一般人群中筛选感染者,并且评估他们传播疾病的风险。.
Keywords: Asymptomatic transmission; COVID-19; Presymptomatic transmission; Source of infection.
Similar articles
-
High proportion of asymptomatic and presymptomatic COVID-19 infections in air passengers to Brunei.J Travel Med. 2020 Aug 20;27(5):taaa066. doi: 10.1093/jtm/taaa066. J Travel Med. 2020. PMID: 32365178 Free PMC article.
-
Presumed Asymptomatic Carrier Transmission of COVID-19.JAMA. 2020 Apr 14;323(14):1406-1407. doi: 10.1001/jama.2020.2565. JAMA. 2020. PMID: 32083643 Free PMC article.
-
Evidence Supporting Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 While Presymptomatic or Asymptomatic.Emerg Infect Dis. 2020 Jul;26(7):e201595. doi: 10.3201/eid2607.201595. Epub 2020 Jun 21. Emerg Infect Dis. 2020. PMID: 32364890 Free PMC article.
-
Surgical Infection Society Guidance for Operative and Peri-Operative Care of Adult Patients Infected by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).Surg Infect (Larchmt). 2020 May;21(4):301-308. doi: 10.1089/sur.2020.101. Epub 2020 Apr 20. Surg Infect (Larchmt). 2020. PMID: 32310715 Review.
-
Asymptomatic SARS Coronavirus 2 infection: Invisible yet invincible.Int J Infect Dis. 2020 Nov;100:112-116. doi: 10.1016/j.ijid.2020.08.076. Epub 2020 Sep 3. Int J Infect Dis. 2020. PMID: 32891737 Free PMC article. Review.
Cited by
-
Factors associated with negative conversion of viral RNA in hospitalized children infected with SARS-CoV-2 Omicron variant in Shanghai, China: a retrospective analysis.BMC Infect Dis. 2023 Apr 26;23(1):264. doi: 10.1186/s12879-023-08223-x. BMC Infect Dis. 2023. PMID: 37101288 Free PMC article.
-
Spatiotemporal analysis and the characteristics of the case transmission network of 2019 novel coronavirus disease (COVID-19) in Zhejiang Province, China.PLoS One. 2021 Sep 17;16(9):e0257587. doi: 10.1371/journal.pone.0257587. eCollection 2021. PLoS One. 2021. PMID: 34534239 Free PMC article.
-
The impact of long-term non-pharmaceutical interventions on COVID-19 epidemic dynamics and control: the value and limitations of early models.Proc Biol Sci. 2021 Aug 25;288(1957):20210811. doi: 10.1098/rspb.2021.0811. Epub 2021 Aug 25. Proc Biol Sci. 2021. PMID: 34428971 Free PMC article.
-
Temperature responsive smart polymer for enabling affinity enrichment of current coronavirus (SARS-CoV-2) to improve its diagnostic sensitivity.Comput Struct Biotechnol J. 2021;19:3609-3617. doi: 10.1016/j.csbj.2021.06.016. Epub 2021 Jun 14. Comput Struct Biotechnol J. 2021. PMID: 34150187 Free PMC article.
-
COVID-19: captures iron and generates reactive oxygen species to damage the human immune system.Autoimmunity. 2021 Jun;54(4):213-224. doi: 10.1080/08916934.2021.1913581. Epub 2021 Apr 26. Autoimmunity. 2021. PMID: 33899609 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources

