Intervention for Iliofemoral Deep Vein Thrombosis and May-Thurner Syndrome

Interv Cardiol Clin. 2020 Apr;9(2):243-254. doi: 10.1016/j.iccl.2019.11.003. Epub 2020 Jan 30.


May-Thurner syndrome, also known as iliac vein compression syndrome, may cause symptoms of venous hypertension and is a predisposing factor for the development of iliofemoral deep vein thrombosis (DVT). Iliofemoral DVT is associated with high rates of development of postthrombotic syndrome, a potentially debilitating condition associated with development of symptoms related to venous outflow obstruction and resulting in reduced quality of life. In this Clinics article, we review procedural intervention with catheter-directed thrombolysis and stenting for iliofemoral DVT and iliac vein compression.

Keywords: Catheter-directed thrombolysis (CDT); Iliac vein compression syndrome; Iliofemoral deep vein thrombosis (DVT); May-Thurner syndrome; Proximal deep vein thrombosis; Venous stenting.

Publication types

  • Review

MeSH terms

  • Femoral Vein*
  • Fibrinolytic Agents / therapeutic use*
  • Humans
  • Iliac Vein*
  • May-Thurner Syndrome / therapy*
  • Thrombolytic Therapy / methods*
  • Vascular Surgical Procedures / methods*
  • Venous Thrombosis / therapy*


  • Fibrinolytic Agents