Strategic use of nanotechnology in drug targeting and its consequences on human health: A focused review

Anand Maurya; Anurag Kumar Singh; Gaurav Mishra; Komal Kumari; Arati Rai; Bhupesh Sharma; Giriraj T Kulkarni; Rajendra Awasthi

doi:10.1556/1646.11.2019.04

Strategic use of nanotechnology in drug targeting and its consequences on human health: A focused review

Interv Med Appl Sci. 2019 Mar;11(1):38-54. doi: 10.1556/1646.11.2019.04.

Authors

Anand Maurya¹, Anurag Kumar Singh², Gaurav Mishra¹, Komal Kumari³, Arati Rai⁴, Bhupesh Sharma⁵, Giriraj T Kulkarni⁵, Rajendra Awasthi⁵

Affiliations

¹ Faculty of Ayurveda, Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
² Centre of Experimental Medicine and Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
³ Department of Pharmacy, School of Chemical Sciences and Pharmacy, Central University of Rajasthan, Ajmer, India.
⁴ Department of Pharmacy, Hygia Institute of Pharmaceutical Education and Research, Lucknow, India.
⁵ Amity Institute of Pharmacy, Amity University, Noida, India.

Abstract

Since the development of first lipid-based nanocarrier system, about 15% of the present pharmaceutical market uses nanomedicines to achieve medical benefits. Nanotechnology is an advanced area to meliorate the delivery of compounds for improved medical diagnosis and curing disease. Nanomedicines are gaining significant interest due to the ultra small size and large surface area to mass ratio. In this review, we discuss the potential of nanotechnology in delivering of active moieties for the disease therapy including their toxicity evidences. This communication will help the formulation scientists in understanding and exploring the new aspects of nanotechnology in the field of nanomedicine.

Keywords: nanocarriers; nanoformulation; nanomedicines; nanotechnology; toxicity.

Publication types

Review

Grants and funding

Funding sources: No financial support was received for this study.