Bidirectional signals of PD-L1 in T cells that fraternize with cancer cells

doi:10.1038/s41590-020-0599-3

Comment

. 2020 Apr;21(4):365-366.

doi: 10.1038/s41590-020-0599-3.

Bidirectional signals of PD-L1 in T cells that fraternize with cancer cells

Rachel M Gibbons Johnson¹, Ti Wen², Haidong Dong³

Affiliations

¹ Biology Discipline, University of Minnesota Morris, Morris, MN, USA.
² Departments of Urology and Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
³ Departments of Urology and Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. dong.haidong@mayo.edu.

PMID: 32152507
DOI: 10.1038/s41590-020-0599-3

Comment

Bidirectional signals of PD-L1 in T cells that fraternize with cancer cells

Rachel M Gibbons Johnson et al. Nat Immunol. 2020 Apr.

. 2020 Apr;21(4):365-366.

doi: 10.1038/s41590-020-0599-3.

Authors

Rachel M Gibbons Johnson¹, Ti Wen², Haidong Dong³

Affiliations

¹ Biology Discipline, University of Minnesota Morris, Morris, MN, USA.
² Departments of Urology and Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
³ Departments of Urology and Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. dong.haidong@mayo.edu.

PMID: 32152507
DOI: 10.1038/s41590-020-0599-3

No abstract available

PubMed Disclaimer

Comment on

PD-L1 engagement on T cells promotes self-tolerance and suppression of neighboring macrophages and effector T cells in cancer.
Diskin B, Adam S, Cassini MF, Sanchez G, Liria M, Aykut B, Buttar C, Li E, Sundberg B, Salas RD, Chen R, Wang J, Kim M, Farooq MS, Nguy S, Fedele C, Tang KH, Chen T, Wang W, Hundeyin M, Rossi JAK, Kurz E, Haq MIU, Karlen J, Kruger E, Sekendiz Z, Wu D, Shadaloey SAA, Baptiste G, Werba G, Selvaraj S, Loomis C, Wong KK, Leinwand J, Miller G. Diskin B, et al. Nat Immunol. 2020 Apr;21(4):442-454. doi: 10.1038/s41590-020-0620-x. Epub 2020 Mar 9. Nat Immunol. 2020. PMID: 32152508

Cited by

Blockade of trans PD-L1 interaction with CD80 augments antitumor immunity.
Zhang Y, Song Q, Cassady K, Lee M, Tang H, Zheng M, Wang B, Schones DE, Fu YX, Riggs AD, Martin PJ, Feng R, Zeng D. Zhang Y, et al. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2205085120. doi: 10.1073/pnas.2205085120. Epub 2023 Apr 10. Proc Natl Acad Sci U S A. 2023. PMID: 37036990 Free PMC article.
Emerging phagocytosis checkpoints in cancer immunotherapy.
Liu Y, Wang Y, Yang Y, Weng L, Wu Q, Zhang J, Zhao P, Fang L, Shi Y, Wang P. Liu Y, et al. Signal Transduct Target Ther. 2023 Mar 7;8(1):104. doi: 10.1038/s41392-023-01365-z. Signal Transduct Target Ther. 2023. PMID: 36882399 Free PMC article. Review.
Blocking of programmed cell death-ligand 1 (PD-L1) expressed on endothelial cells promoted the recruitment of CD8⁺IFN-γ⁺ T cells in atherosclerosis.
Li Q, Wei S, Li Y, Wu F, Qin X, Li Z, Li J, Chen C. Li Q, et al. Inflamm Res. 2023 Apr;72(4):783-796. doi: 10.1007/s00011-023-01703-5. Epub 2023 Mar 3. Inflamm Res. 2023. PMID: 36867228
A Novel Humanized PD-1/PD-L1 Mouse Model Permits Direct Comparison of Antitumor Immunity Generated by Food and Drug Administration-Approved PD-1 and PD-L1 Inhibitors.
Barham W, Hsu M, Liu X, Harrington SM, Hirdler JB, Gicobi JK, Zhu X, Zeng H, Pavelko KD, Yan Y, Mansfield AS, Dong H. Barham W, et al. Immunohorizons. 2023 Jan 1;7(1):125-139. doi: 10.4049/immunohorizons.2200054. Immunohorizons. 2023. PMID: 36656137 Free PMC article.
Therapeutic targeting of PD-1/PD-L1 blockade by novel small-molecule inhibitors recruits cytotoxic T cells into solid tumor microenvironment.
Acúrcio RC, Pozzi S, Carreira B, Pojo M, Gómez-Cebrián N, Casimiro S, Fernandes A, Barateiro A, Farricha V, Brito J, Leandro AP, Salvador JAR, Graça L, Puchades-Carrasco L, Costa L, Satchi-Fainaro R, Guedes RC, Florindo HF. Acúrcio RC, et al. J Immunother Cancer. 2022 Jul;10(7):e004695. doi: 10.1136/jitc-2022-004695. J Immunother Cancer. 2022. PMID: 35863821 Free PMC article.

See all "Cited by" articles

References

1. Dong, H. & Chen, L. J. Mol. Med. 81, 281–287 (2003). - DOI
1. Diskin. B. et al. Nat. Immunol. https://doi.org/10.1038/s41590-020-0620-x (2020).
1. Dong, H., Zhu, G., Tamada, K. & Chen, L. Nat. Med. 5, 1365–1369 (1999). - DOI
1. Keir, M. E., Butte, M. J., Freeman, G. J. & Sharpe, A. H. Annu. Rev. Immunol. 26, 677–704 (2008). - DOI
1. Herbst, R. S. et al. Nature 515, 563–567 (2014). - DOI

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions

LinkOut - more resources

Full Text Sources
- Nature Publishing Group
Research Materials
- NCI CPTC Antibody Characterization Program

[1] Dong, H. & Chen, L. J. Mol. Med. 81, 281–287 (2003). - DOI

[2] Dong, H. & Chen, L. J. Mol. Med. 81, 281–287 (2003). - DOI

[3] Diskin. B. et al. Nat. Immunol. https://doi.org/10.1038/s41590-020-0620-x (2020).

[4] Diskin. B. et al. Nat. Immunol. https://doi.org/10.1038/s41590-020-0620-x (2020).

[5] Dong, H., Zhu, G., Tamada, K. & Chen, L. Nat. Med. 5, 1365–1369 (1999). - DOI

[6] Dong, H., Zhu, G., Tamada, K. & Chen, L. Nat. Med. 5, 1365–1369 (1999). - DOI

[7] Keir, M. E., Butte, M. J., Freeman, G. J. & Sharpe, A. H. Annu. Rev. Immunol. 26, 677–704 (2008). - DOI

[8] Keir, M. E., Butte, M. J., Freeman, G. J. & Sharpe, A. H. Annu. Rev. Immunol. 26, 677–704 (2008). - DOI

[9] Herbst, R. S. et al. Nature 515, 563–567 (2014). - DOI

[10] Herbst, R. S. et al. Nature 515, 563–567 (2014). - DOI

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Bidirectional signals of PD-L1 in T cells that fraternize with cancer cells

Affiliations

Bidirectional signals of PD-L1 in T cells that fraternize with cancer cells

Authors

Affiliations

Comment on

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Research Materials