Hypolipidaemic effects of Curcuma longa L and Nardostachys jatamansi, DC in triton-induced hyperlipidaemic rats

Indian J Physiol Pharmacol. 1988 Oct-Dec;32(4):299-304.

Abstract

Fifty per cent ethanolic extract of Curcuma longa (tuber) and Nardostachys jatamansi (whole plant) feeding elevates HDL-cholesterol/total cholesterol ratio. The extracts also caused a significant reduction in the ratio of total cholesterol/phospholipids. Curcuma longa exhibited better cholesterol and triglyceride lowering activity [Ch = -85%; Tg = -88%] as compared to N. jatamansi in triton-induced hyperlipidaemic rats. In view of the protective action of HDL against heart disease and atherogenecity, C. longa consumption is recommended.

MeSH terms

  • Animals
  • Cholesterol / blood
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Cholesterol, VLDL / blood
  • Hyperlipidemias / blood
  • Hyperlipidemias / chemically induced
  • Hyperlipidemias / drug therapy*
  • Hypolipidemic Agents*
  • Male
  • Medicine, Ayurvedic
  • Plant Extracts / pharmacology
  • Plants, Medicinal*
  • Polyethylene Glycols
  • Rats

Substances

  • Cholesterol, HDL
  • Cholesterol, LDL
  • Cholesterol, VLDL
  • Hypolipidemic Agents
  • Plant Extracts
  • Polyethylene Glycols
  • Cholesterol
  • tyloxapol