Introduction: A vast range of factors cause adverse outcomes after coronary surgery. The goal of this study was to figure out if there was a relation between large volumes of fluid balance in patients who underwent coronary surgery and common complications after CABG.
Methods: 130 candidates for on-pump CABG were enrolled in our study at Rajaie Cardiovascular Medical and Research Center in 2016. After calculating balance volume for each patient, they were divided into 3 groups; Group (1): fluid balance < 2000 mL, Group (2): fluid balance 2000-3000 mL, Group (3): fluid balance > 3000 mL. Some of the post-surgery complications were studied in these 3 groups. Since in similar studies, fluid overload has been investigated based on the patient's weight gain after surgery or only on the basis of the patient's fluid intake, we designed a study based on an accurate fluid balance measurement, which included the subtraction of the patient's outputs and losses from their intakes.
Results: Logistic Regression showed that fluid balance > 3000ml was the predictor of long mechanical ventilation [ (Odds Ratio (95% CI) = 4.6 (1.9 - 11.5), P < .05], more than 3 days of ICU stay [(Odds Ratio (95% CI) = 3.2 (1.09 - 9.6), P < .05], and longer hospital stay [Odds Ratio (95% CI) = 5.2 (1.9 - 14.08), P < .05]. There was no significant relation between AKI and fluid balance.
Conclusion: Administration of large fluid volumes in CABG patients would lead to fluid accumulation and independently associated with prolonged mechanical ventilation, longer ICU stays and extended hospital stays.