Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Mar 12;10.1002/jmv.25757.
doi: 10.1002/jmv.25757. Online ahead of print.

COVID-19 Patients' Clinical Characteristics, Discharge Rate, and Fatality Rate of Meta-Analysis

Free PMC article

COVID-19 Patients' Clinical Characteristics, Discharge Rate, and Fatality Rate of Meta-Analysis

Long-Quan Li et al. J Med Virol. .
Free PMC article


The aim of this study was to analyze the clinical data, discharge rate, and fatality rate of COVID-19 patients for clinical help. The clinical data of COVID-19 patients from December 2019 to February 2020 were retrieved from four databases. We statistically analyzed the clinical symptoms and laboratory results of COVID-19 patients and explained the discharge rate and fatality rate with a single-arm meta-analysis. The available data of 1994 patients in 10 literatures were included in our study. The main clinical symptoms of COVID-19 patients were fever (88.5%), cough (68.6%), myalgia or fatigue (35.8%), expectoration (28.2%), and dyspnea (21.9%). Minor symptoms include headache or dizziness (12.1%), diarrhea (4.8%), nausea and vomiting (3.9%). The results of the laboratory showed that the lymphocytopenia (64.5%), increase of C-reactive protein (44.3%), increase of lactic dehydrogenase (28.3%), and leukocytopenia (29.4%) were more common. The results of single-arm meta-analysis showed that the male took a larger percentage in the gender distribution of COVID-19 patients 60% (95% CI [0.54, 0.65]), the discharge rate of COVID-19 patients was 52% (95% CI [0.34,0.70]), and the fatality rate was 5% (95% CI [0.01,0.11]).

Keywords: 2019-nCoV; COVID-19; clinical characteristics; discharge rate; fatality rate; meta-analysis.

Conflict of interest statement

The authors declare that there are no conflict of interests.


Figure 1
Figure 1
A flow diagram of the inclusion criteria of studies eligible for meta‐analysis
Figure 2
Figure 2
Forest plot of all the outcomes. (A, C, E) sex distribution; fatality rate; discharge rate. Funnel plot (B, D, F) sex distribution; fatality rate; discharge rate

Similar articles

See all similar articles

Cited by 17 articles

See all "Cited by" articles


    1. National Health Commission of the People's Republic of China main website. Accessed 20 January 2020.
    1. WHO main website. Accessed 5 February 2020.
    1. Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727‐733. - PMC - PubMed
    1. Zhou P, Yang XL, Wang XG, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579:270‐273. - PMC - PubMed
    1. Yang Y, Lu Q, Liu M, et al. Epidemiological and clinical features of the 2019 novel coronavirus outbreak in China. 2020.

LinkOut - more resources