Electrohypersensitivity as a Newly Identified and Characterized Neurologic Pathological Disorder: How to Diagnose, Treat, and Prevent It

Int J Mol Sci. 2020 Mar 11;21(6):1915. doi: 10.3390/ijms21061915.


Since 2009, we built up a database which presently includes more than 2000 electrohypersensitivity (EHS) and/or multiple chemical sensitivity (MCS) self-reported cases. This database shows that EHS is associated in 30% of the cases with MCS, and that MCS precedes the occurrence of EHS in 37% of these EHS/MCS-associated cases. EHS and MCS can be characterized clinically by a similar symptomatic picture, and biologically by low-grade inflammation and an autoimmune response involving autoantibodies against O-myelin. Moreover, 80% of the patients with EHS present with one, two, or three detectable oxidative stress biomarkers in their peripheral blood, meaning that overall these patients present with a true objective somatic disorder. Moreover, by using ultrasonic cerebral tomosphygmography and transcranial Doppler ultrasonography, we showed that cases have a defect in the middle cerebral artery hemodynamics, and we localized a tissue pulsometric index deficiency in the capsulo-thalamic area of the temporal lobes, suggesting the involvement of the limbic system and the thalamus. Altogether, these data strongly suggest that EHS is a neurologic pathological disorder which can be diagnosed, treated, and prevented. Because EHS is becoming a new insidious worldwide plague involving millions of people, we ask the World Health Organization (WHO) to include EHS as a neurologic disorder in the international classification of diseases.

Keywords: O-myelin; electrohypersensibility; electromagnetic fields; extremely low frequency; histamine; inflammation; melatonin; multiple chemical sensitivity; neurologic disease; oxidative stress; radiofrequency.

Publication types

  • Review

MeSH terms

  • Biomarkers / blood*
  • Electromagnetic Fields / adverse effects
  • Humans
  • Middle Cerebral Artery / diagnostic imaging
  • Middle Cerebral Artery / metabolism
  • Multiple Chemical Sensitivity / complications
  • Multiple Chemical Sensitivity / diagnostic imaging*
  • Multiple Chemical Sensitivity / metabolism
  • Nervous System Diseases / diagnostic imaging*
  • Nervous System Diseases / etiology
  • Nervous System Diseases / metabolism
  • Oxidative Stress
  • Self Report
  • Ultrasonography, Doppler, Transcranial


  • Biomarkers