Orbital and conjunctival lymphoma treatment and prognosis

Radiother Oncol. 1988 Dec;13(4):237-44. doi: 10.1016/0167-8140(88)90218-6.


115 patients with lymphoid tumours presenting in the orbit were seen between 1970 and 1984. The histological types were high-grade malignant lymphoma--18, low-grade malignant lymphoma--43, and indeterminate lymphocytic lesions--54. Eighteen patients were found to have disseminated lymphoma at presentation. The majority of the patients received radiotherapy to the orbit; local control was achieved in all cases and the ocular morbidity from radiotherapy was low with 11 patients developing lens opacities and 5 a dry eye. Survival of patients with stage I low-grade lymphoma and indeterminate lymphocytic lesions was similar to that of a normal population of the same age distribution. The clinic features and dissemination pattern of the low-grade malignant lymphomata and the indeterminate lymphocytic lesions were identical, suggesting that most, if not all, lymphoid masses presenting in the orbit are neoplastic rather than reactive in nature.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Child, Preschool
  • Conjunctival Neoplasms / mortality
  • Conjunctival Neoplasms / radiotherapy*
  • Female
  • Humans
  • Lymphoma / mortality
  • Lymphoma / radiotherapy*
  • Male
  • Middle Aged
  • Orbital Neoplasms / mortality
  • Orbital Neoplasms / radiotherapy*
  • Prognosis
  • Radiotherapy Dosage