Influence of household smoking habits on inhalation bioaccessibility of trace elements and light rare earth elements in Canadian house dust

Farzana Kastury; Susie Ritch; Pat E Rasmussen; Albert L Juhasz

doi:10.1016/j.envpol.2020.114132

Influence of household smoking habits on inhalation bioaccessibility of trace elements and light rare earth elements in Canadian house dust

Environ Pollut. 2020 Jul:262:114132. doi: 10.1016/j.envpol.2020.114132. Epub 2020 Feb 6.

Authors

Farzana Kastury¹, Susie Ritch², Pat E Rasmussen³, Albert L Juhasz²

Affiliations

¹ Future Industries Institute, University of South Australia, Mawson Lakes Campus, Adelaide, SA, 5095, Australia. Electronic address: farzana.kastury@mymail.unisa.edu.au.
² Future Industries Institute, University of South Australia, Mawson Lakes Campus, Adelaide, SA, 5095, Australia.
³ Exposure and Biomonitoring Division, Environmental Health Science and Research Bureau, HECSB, Health Canada, Ottawa, ON, Canada.

PMID: 32179218
DOI: 10.1016/j.envpol.2020.114132

Abstract

In this study, total concentration and inhalation bioaccessibility (dissolution in simulated biological solution) of trace elements (TE) and rare earth elements (REE) were assessed in PM₁₀ from Canadian house dust samples with smoking (n = 25) and non-smoking (n = 25) status. Compared to the natural background concentrations in Canadian soils, median Zn, Pb, Cd and Cu concentrations in PM₁₀ were 10-23 fold higher, while median La, Ce and Pr concentrations were 1.6-2.4 fold higher. Mann-Whitney tests (α = 0.05) indicated no difference between the median TE concentrations based on the smoking status of the household; however, median REE concentrations were significantly higher in the PM₁₀ of smoking households. Additionally, Cd and Ni were positively correlated (Spearman r, p < 0.05) to La, Ce and Nd in smoking households, suggesting that tobacco combustion may have contributed REE in the PM₁₀ of these households. Median inhalation-ingestion bioaccessibility assay outcomes of arsenic (As) and lead (Pb) was higher in the non-smoking households when compared to smoking households (Mann Whitney test, α = 0.05), suggesting that tobacco combustion products may be associated with less soluble species of As and Pb. Although REE bioaccessibility was negligible in simulated lung epithelial fluid regardless of the smoking status of the household, bioaccessibility in the lung-gastric phase was 23.6-27.6% in the smoking household and 34.7-36.7% in the non-smoking households, indicating a significantly lower REE dissolution in PM₁₀ of smoking households. In contrast, between 17 and 21.9% bioaccessibility of REE was observed when artificial lysosomal fluid was used, where the outcome was not significantly affected by the smoking status. This study indicates that despite a higher median REE concentration in the PM₁₀ of smoking households, inhalation bioaccessibility may be significantly influenced by the mineralogy.

Keywords: ALF; Lanthanides; Lung bioaccessibility; Resuspended dust; Trace metals.

MeSH terms

Canada
Dust / analysis
Habits
Metals, Rare Earth*
Trace Elements*

Substances

Dust
Metals, Rare Earth
Trace Elements