Perinatal Transmission of 2019 Coronavirus Disease-Associated Severe Acute Respiratory Syndrome Coronavirus 2: Should We Worry?

Clin Infect Dis. 2021 Mar 1;72(5):862-864. doi: 10.1093/cid/ciaa226.


We present 2 cases of coronavirus disease 2019 (COVID-19)-associated severe respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during the third trimester of pregnancy. Both mothers and newborns had excellent outcomes. We failed to identify SARS-CoV-2 in all of the products of conception and the newborns. This report provided evidence of low risk of intrauterine infection by vertical transmission of SARS-CoV-2.

Keywords: COVID-19; SARS-CoV-2; pregnancy outcome; vertical transmission.

MeSH terms

  • COVID-19*
  • Coronavirus*
  • Female
  • Humans
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical
  • Pregnancy
  • Pregnancy Complications, Infectious*
  • Pregnancy Outcome
  • SARS-CoV-2