Perinatal Transmission of 2019 Coronavirus Disease-Associated Severe Acute Respiratory Syndrome Coronavirus 2: Should We Worry?

Cuifang Fan; Di Lei; Congcong Fang; Chunyan Li; Ming Wang; Yuling Liu; Yan Bao; Yanmei Sun; Jinfa Huang; Yuping Guo; Ying Yu; Suqing Wang

doi:10.1093/cid/ciaa226

Perinatal Transmission of 2019 Coronavirus Disease-Associated Severe Acute Respiratory Syndrome Coronavirus 2: Should We Worry?

Clin Infect Dis. 2021 Mar 1;72(5):862-864. doi: 10.1093/cid/ciaa226.

Authors

Cuifang Fan¹, Di Lei¹, Congcong Fang², Chunyan Li¹, Ming Wang³, Yuling Liu¹, Yan Bao¹, Yanmei Sun¹, Jinfa Huang¹, Yuping Guo¹, Ying Yu¹, Suqing Wang⁴

Affiliations

¹ Department of Obstetrics, Renmin Hospital of Wuhan University, Hubei, Wuhan, China.
² Department of Pediatrics, Renmin Hospital of Wuhan University, Hubei, Wuhan, China.
³ Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Hubei, Wuhan, China.
⁴ Department of Preventive Medicine, School of Health Sciences, Wuhan University, Hubei, Wuhan, China.

Abstract

We present 2 cases of coronavirus disease 2019 (COVID-19)-associated severe respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during the third trimester of pregnancy. Both mothers and newborns had excellent outcomes. We failed to identify SARS-CoV-2 in all of the products of conception and the newborns. This report provided evidence of low risk of intrauterine infection by vertical transmission of SARS-CoV-2.

Keywords: COVID-19; SARS-CoV-2; pregnancy outcome; vertical transmission.

MeSH terms

COVID-19*
Coronavirus*
Female
Humans
Infant, Newborn
Infectious Disease Transmission, Vertical
Pregnancy
Pregnancy Complications, Infectious*
Pregnancy Outcome
SARS-CoV-2