SARS-CoV-2 and COVID-19: The most important research questions

Kit-San Yuen; Zi-Wei Ye; Sin-Yee Fung; Chi-Ping Chan; Dong-Yan Jin

doi:10.1186/s13578-020-00404-4

SARS-CoV-2 and COVID-19: The most important research questions

Cell Biosci. 2020 Mar 16:10:40. doi: 10.1186/s13578-020-00404-4. eCollection 2020.

Authors

Kit-San Yuen¹, Zi-Wei Ye², Sin-Yee Fung¹, Chi-Ping Chan¹, Dong-Yan Jin¹

Affiliations

¹ 1School of Biomedical Sciences, The University of Hong Kong, 3/F Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong.
² 2Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong.

Abstract

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Here we highlight nine most important research questions concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccine development, origin of virus and viral pathogenesis.

Keywords: 2019 novel coronavirus (2019-nCoV); COVID-19; Novel coronavirus pneumonia (NCP); SARS-CoV-2.