Transmission of COVID-19 in the terminal stages of the incubation period: A familial cluster

Int J Infect Dis. 2020 Jul;96:452-453. doi: 10.1016/j.ijid.2020.03.027. Epub 2020 Mar 16.


We report a familial cluster of 2019 novel coronavirus disease (COVID-19) to assess its potential transmission during the incubation period. The first patient in this familial cluster was identified during the presymptomatic period, as a close contact of a confirmed patient. Five family members had close contact with this first patient during his incubation period, with four of them confirmed positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the subsequent sampling tests.

Keywords: COVID-19; Cluster; Incubation period; SARS-CoV-2.

MeSH terms

  • Adult
  • Aged
  • Betacoronavirus*
  • COVID-19
  • Child
  • Coronavirus Infections / transmission*
  • Family
  • Female
  • Humans
  • Infectious Disease Incubation Period*
  • Male
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / transmission*
  • SARS-CoV-2