The life-threatening eruption in HIV and immunosuppression

Clin Dermatol. 2020 Jan-Feb;38(1):52-62. doi: 10.1016/j.clindermatol.2019.10.014. Epub 2019 Nov 16.


Immunosuppressed patients frequently have skin diseases of mild to moderate intensity. Diagnosis as well as treatment should be performed early to avoid important complications for these patients. Skin eruptions are among these problems. Life-threatening eruptions in HIV and other types of immunosuppression range from acute retroviral syndrome to drug eruptions; immune reconstitution inflammatory syndrome; infection by virus, protozoan, bacteria, or fungi; inflammatory and immune dermatoses; and neoplasia. All of these are discussed in this group of patients.

Publication types

  • Review

MeSH terms

  • Acute Retroviral Syndrome / complications
  • Bacterial Infections / complications
  • Drug Eruptions / etiology
  • Drug Eruptions / pathology
  • HIV Infections / complications*
  • Humans
  • Immunocompromised Host*
  • Inflammation / complications
  • Mycoses / complications
  • Neoplasms / complications
  • Parasitic Diseases / complications
  • Skin Diseases / etiology*
  • Skin Diseases / pathology