Syncope in the Young Adult and in the Athlete: Causes and Clinical Work-up to Exclude a Life-Threatening Cardiac Disease

J Cardiovasc Transl Res. 2020 Jun;13(3):322-330. doi: 10.1007/s12265-020-09989-0. Epub 2020 Mar 20.

Abstract

Syncope is defined as a transient loss of consciousness due to cerebral hypoperfusion, characterized by a rapid onset, short duration, and spontaneous complete recovery. It is usually a benign event, but sometimes it may represent the initial presentation of several cardiac disorders associated with sudden cardiac death during physical activity. A careful evaluation is essential particularly in young adults and in competitive athletes in order to exclude the presence of an underlying life-threatening cardiovascular disease. The present review analyzes the main non-cardiac and cardiac causes of syncope and the contribution of the available tools for differential diagnosis. Clinical work-up of the athlete with syncope occurring in extreme environments and management in terms of sports eligibility and disqualification are also discussed.

Keywords: Cardiomyopathies; Faint; Pre-syncope; Sports cardiology; Sudden death; Ventricular arrhythmias.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Arrhythmias, Cardiac / complications
  • Arrhythmias, Cardiac / diagnosis*
  • Arrhythmias, Cardiac / mortality
  • Arrhythmias, Cardiac / therapy
  • Athletes*
  • Cardiomyopathies / complications
  • Cardiomyopathies / diagnostic imaging*
  • Cardiomyopathies / mortality
  • Cardiomyopathies / therapy
  • Death, Sudden, Cardiac / etiology*
  • Death, Sudden, Cardiac / prevention & control
  • Diagnosis, Differential
  • Humans
  • Physical Endurance
  • Prognosis
  • Risk Assessment
  • Risk Factors
  • Syncope / etiology*
  • Young Adult