Bilateral Synchronous Testicular Germ Cell Tumors in Children: Case Report and Review of the Literature

Urology. 2020 Jun:140:155-158. doi: 10.1016/j.urology.2020.03.012. Epub 2020 Mar 18.

Abstract

Bilateral testicular tumors are very rare in pediatric patients and only a few case reports have been reported. These patients have a high risk of sterility due to bilateral orchiectomy and subsequent gonadotoxic treatments. Therefore, if possible, testis-sparing surgery should be performed in patients with benign masses and testicular tissue preservation may be recommended in order to maintain fertility in later life. We present a 23 months old boy with synchronous bilateral testicular tumor managed with unilateral orchiectomy and testis-sparing surgery and testicular tissue cryopreservation performed to the controlateral side. We also review the literature on bilateral testis tumors in children.

Publication types

  • Case Reports

MeSH terms

  • Cryopreservation / methods*
  • Humans
  • Infant
  • Male
  • Neoplasms, Germ Cell and Embryonal* / blood
  • Neoplasms, Germ Cell and Embryonal* / pathology
  • Neoplasms, Germ Cell and Embryonal* / surgery
  • Neoplasms, Multiple Primary* / blood
  • Neoplasms, Multiple Primary* / pathology
  • Neoplasms, Multiple Primary* / surgery
  • Orchiectomy / methods*
  • Organ Sparing Treatments / methods*
  • Teratoma* / blood
  • Teratoma* / pathology
  • Teratoma* / surgery
  • Testicular Neoplasms* / blood
  • Testicular Neoplasms* / pathology
  • Testicular Neoplasms* / surgery
  • Testis* / diagnostic imaging
  • Testis* / pathology
  • Testis* / surgery
  • Tissue Preservation / methods
  • Treatment Outcome
  • Ultrasonography / methods
  • alpha-Fetoproteins / analysis

Substances

  • alpha-Fetoproteins

Supplementary concepts

  • Testicular Germ Cell Tumor