Cervical cancer patterns of care in Italy: A radiation oncology survey of MITO and AIRO GYN groups

Crit Rev Oncol Hematol. 2020 May:149:102925. doi: 10.1016/j.critrevonc.2020.102925. Epub 2020 Mar 3.

Abstract

Large heterogeneity in therapeutic approaches to cervical cancer (CC) patients has been registered worldwide; a national survey exploring practice settings and equipments in CC treatment was distributed to radiation oncologists. Questionnaires were compiled in 90 of 194 Centers (compliance: 46.3 %). Most of respondents reported the presence of multidisciplinary tumor board, and modern equipments/techniques; 55.5 % of centers reported >1 brachytherapy (BT) equipment, thus implying the need to refer their patients outside for the remaining centers. Post-surgery radiotherapy was performed in 96.7 % of early CC (ECC) cases with pathological high risk factors. Exclusive chemoradiation with concomitant platinum schedules was referred to be used by 84.4 % of centers in locally advanced CC. Alternative options were reported with a range between 4.4 and 28.9 %. The present survey reports a broad spectrum of therapeutic options for CC in Italy. Availability and use of modern techniques is quite diffuse, but the distribution of BT resources and skills remains a challenge.

Keywords: Cervical cancer; Chemoradiation; Pattern of care; Personalized medicine; Survey.

MeSH terms

  • Brachytherapy*
  • Chemoradiotherapy*
  • Female
  • Humans
  • Italy
  • Practice Patterns, Physicians'
  • Precision Medicine
  • Radiation Oncology*
  • Surveys and Questionnaires
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / therapy*