The distribution of estradiol in the sera of normal Caucasian, Chinese, Filipina, Hawaiian and Japanese women living in Hawaii

Eur J Cancer Clin Oncol. 1988 Dec;24(12):1855-60. doi: 10.1016/0277-5379(88)90098-3.


Mean concentrations of sex-hormone-binding-globulin (SHBG) and the percentage distribution of estradiol between the non-protein-bound, albumin-bound and SHBG-bound fractions were not different in Caucasian, Hawaiian, Chinese, Japanese and Filipinas living in Hawaii. The widely varying incidence rates for breast cancer are therefore not explained by variations in the availability of estradiol.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Body Height
  • Body Weight
  • China / ethnology
  • Continental Population Groups*
  • Estradiol / blood*
  • European Continental Ancestry Group
  • Female
  • Hawaii
  • Humans
  • Japan / ethnology
  • Menopause
  • Middle Aged
  • Philippines / ethnology
  • Serum Albumin / metabolism
  • Sex Hormone-Binding Globulin


  • Serum Albumin
  • Sex Hormone-Binding Globulin
  • Estradiol