Finding the Pathway: Mediation Analyses in Randomized Controlled Trials

Ann Intern Med. 2020 Apr 21;172(8):553-557. doi: 10.7326/M20-0887. Epub 2020 Mar 24.

Authors

A Russell Localio¹, Anne R Meibohm², Eliseo Guallar³

Affiliations

¹ University of Pennsylvania, Philadelphia, Pennsylvania (A.R.L.).
² American College of Physicians, Philadelphia, Pennsylvania (A.R.M.).
³ Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (E.G.).

PMID: 32203981
DOI: 10.7326/M20-0887

No abstract available

MeSH terms

Anemia / drug therapy*
Antibodies, Monoclonal, Humanized / therapeutic use*
C-Reactive Protein / analysis
Data Interpretation, Statistical*
Humans
Interleukin-1beta / antagonists & inhibitors*
Models, Statistical*
Randomized Controlled Trials as Topic / methods*

Substances

Antibodies, Monoclonal, Humanized
IL1B protein, human
Interleukin-1beta
canakinumab
C-Reactive Protein