KIE: Commentators from Scotland (A.G.M. Campbell), Portugal (C.P. Correia), Japan (H. Kawashima), and Nigeria (E.O. Ekunwe) discuss a case study involving a man with radial aplasia thrombocytopenia syndrome (TAR) who married a cousin whose brother has TAR. His wife is pregnant, and the couple has sought guidance from a university hospital's genetics clinic in an unidentified city and country. Each commentator discusses the options of genetic counseling, prenatal diagnosis, and selective abortion in the context of his or her country's attitude and policies toward the handicapped, its regulation of abortion, and the availability of public health services.