Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection exported from mainland China could lead to self-sustained outbreaks in other countries. By February 2020, several countries were reporting imported SARS-CoV-2 cases. To contain the virus, early detection of imported SARS-CoV-2 cases is critical. We used air travel volume estimates from Wuhan, China, to international destinations and a generalized linear regression model to identify locations that could have undetected imported cases. Our model can be adjusted to account for exportation of cases from other locations as the virus spreads and more information on importations and transmission becomes available. Early detection and appropriate control measures can reduce the risk for transmission in all locations.
Keywords: 2019 novel coronavirus disease; COVID-19; SARS-CoV-2; coronavirus; outbreak; pneumonia; respiratory infections; severe acute respiratory syndrome coronavirus 2; travelers health; viruses; zoonoses.
Features, Evaluation and Treatment Coronavirus (COVID-19).2020 Apr 6. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan–. StatPearls. 2020 Jan–. PMID: 32150360 Free Books & Documents. Review.
Early Introduction of Severe Acute Respiratory Syndrome Coronavirus 2 into Europe.Emerg Infect Dis. 2020 Mar 20;26(7). doi: 10.3201/eid2607.200359. Online ahead of print. Emerg Infect Dis. 2020. PMID: 32197059
Early estimation of the case fatality rate of COVID-19 in mainland China: a data-driven analysis.Ann Transl Med. 2020 Feb;8(4):128. doi: 10.21037/atm.2020.02.66. Ann Transl Med. 2020. PMID: 32175421 Free PMC article.
Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and myths.J Microbiol Immunol Infect. 2020 Mar 4. doi: 10.1016/j.jmii.2020.02.012. Online ahead of print. J Microbiol Immunol Infect. 2020. PMID: 32173241 Free PMC article. Review.
Quantifying the improvement in confirmation efficiency of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the early phase of the outbreak in Hong Kong in 2020.Int J Infect Dis. 2020 May 8;96:284-287. doi: 10.1016/j.ijid.2020.05.015. Online ahead of print. Int J Infect Dis. 2020. PMID: 32413609 Free PMC article.
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