Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Mar 9;12:71-78.
doi: 10.2147/CCIDE.S230809. eCollection 2020.

Plaque Fluoride Levels as a Predictor of Caries Development in Early Childhood With High Sugar Exposure - A Preliminary Study

Affiliations
Free PMC article

Plaque Fluoride Levels as a Predictor of Caries Development in Early Childhood With High Sugar Exposure - A Preliminary Study

Karina Ferreira Rizzardi et al. Clin Cosmet Investig Dent. .
Free PMC article

Abstract

Objective: This longitudinal study aimed to investigate if the plaque fluoride (PF) concentration can predict the early childhood caries onset. Design: As part of a larger study, 188 preschoolers were clinically evaluated for early childhood caries diagnosis, at baseline and after 1-year follow-up. After that, the final sample comprised: 1. children who had already caries at baseline (decayed, missing or filled surfaces, as well as white chalky white spot lesions adjacent to gingival margins) and developed at least one more cavitation after one year (n=16), and 2. children who never had or developed any caries lesions, including active white spots lesions (n=15). Before the clinical examinations, dental plaque was collected. PF concentration was determined with an ion-specific electrode. A chart was used to estimate the mean daily sugar exposure. The results were statistically analyzed by Spearman correlation and logistic regression analyses (α=0.05).

Results: After one year, a positive significant correlation between caries development and liquid sucrose, total sugar and total sucrose consumption increments was found (p<0.05). Moreover, the solid sugar, solid sucrose and total sugar exposure at baseline were positively correlated with the presence of dental plaque at follow-up (p<0.05). To top it all, children with PF concentrations ≤0.1 μg/mg at baseline were 10 times more likely to develop caries.

Conclusion: In conclusion, this study demonstrated for the first time in vivo that low PF concentration is a predictor of caries development in primary teeth.

Keywords: biofilm; dental caries; fluoride; preschool child.

Conflict of interest statement

The author reports no conflicts of interest in this work.

Similar articles

See all similar articles

References

    1. Bayrak S, Okte Z, Fidanci UR. Relationship between caries and dental plaque composition. Am J Dent. 2011;24:45–48. - PubMed
    1. Buzalaf MA, Pessan JP, Honório HM, Ten Cate JM. Mechanisms of action of fluoride for caries control. Monogr Oral Sci. 2011;22:97–114. - PubMed
    1. Ccahuana-Vasquez RA, Tabchoury CP, Tenuta LM, Del Bel Cury AA, Vale GC, Cury JA. Effect of frequency of sucrose exposure on dental biofilm composition and enamel demineralization in the presence of fluoride. Caries Res. 2007;41(1):9–15. doi:10.1159/000096100 - DOI - PubMed
    1. Cury JA, Tenuta LM. Enamel remineralization: controlling the caries disease or treating early caries lesions? Braz Oral Res. 2009;23(Suppl 1):23–30. doi:10.1590/S1806-83242009000500005 - DOI - PubMed
    1. Featherstone JD, Glena R, Shariati M, Shields CP. Dependence of in vitro demineralization of apatite and remineralization of dental enamel on fluoride concentration. J Dent Res. 1990;69:620–625. doi:10.1177/00220345900690S121 - DOI - PubMed

Grant support

This work was financially supported by FAPESP under Grant 2008/09510-3; and CNPq under Grant 480401/2008-0.

LinkOut - more resources

Feedback